Nu-Tek BioSciences is the market leader in animal-free yeast extracts, peptones, and hydrolysates. Based in the US and a key partner for global pharmaceutical and biotechnology companies, our quality products and manufacturing capabilities are ready to meet your production needs.

Nu-Tek serves global pharmaceutical, biotech, and industrial fermentation customers. We ensure that all quality, regulatory, and supply chain requirements are met, supporting the production of breakthrough therapeutics today and into the future.

Nu-Tek BioSciences is headquartered in Minnetonka, Minnesota. Our manufacturing facility is based in Austin, Minnesota with direct access to a variety of shipping routes. We serve pharmaceutical and biotech leaders worldwide with our expertise, supply chain security, and global distribution abilities.

Nu-Tek serves customers globally, both directly as well as through our international distribution partners. Contact us to learn more about our distribution capabilities.

Peptones (hydrolysates) are a complex mixture of polypeptides and free amino acids as well as carbohydrates, salts/trace minerals, and vitamins critical for cell nutrition.³ Peptones are generally produced through the enzymatic hydrolysis of a protein source.^1,2 Depending on the use, peptones are considered GRAS or regulated as a food additive.

While peptones can be considered more variable than chemically defined media additives, Nu-Tek’s approach to peptone production controls this biological variability through a state-of-the-art, proprietary manufacturing process, as well as our Variability Reduction Program (VRP).

Nu-Tek’s peptones (hydrolysates) and yeast extracts are critical to cell culture and fermentation processes used across the biotechnology, pharmaceutical, and industrial fermentation sectors. Nu-Tek’s products can be leveraged to supplement existing culture media to improve performance, or as a replacement for animal-based nutrient sources (such as Fetal Bovine Serum (FBS) or Casein). 

Yes, Nu-Tek’s Yeast Extract products are enzyme-hydrolyzed, autolyzed yeast similar to what other suppliers refer to as a yeastolate.  The exact yeast extract product will vary by application.  Contact our team to help determine the best product for your application.

Animal-free culture media provides multiple benefits, including improving product consistency, removing the risk of cross-contamination with adventitious agents such as viruses or TSE/BSE, and avoiding supply chain shortages. Demand for animal-free raw materials is increasing globally as new regulations, sustainability requirements, and ethical concerns become integral to the biopharma production process.

Yes, many of Nu-Tek’s products are certified Halal by the Islamic Food and Nutrition Council of America (IFANCA). Halal certification for raw materials is critical to ensure our customers can meet global regulatory and cultural requirements regardless of the markets they serve.

Yes, many of Nu-Tek’s products are certified Kosher by United Mehadrin Kosher. Kosher certification supports customers who serve markets that require Kosher raw materials in pharmaceutical, cosmetic, and food production.

Many of Nu-Tek’s products are certified Organic to meet customer regulatory, sustainability, and quality requirements. Customers may also require Organic certification to expand the use of Nu-Tek’s products within various product lines for human or animal consumption.

Nu-Tek has received and maintained multiple certifications for its facility and products, including ISO 9001:2015, EcoVadis, Halal, Kosher, and Organic statuses. These certifications are critical to our business as well as the goals and requirements of our customers.

Nu-Tek’s primary focus is to support customer quality and regulatory requirements. We are FDA-compliant and have many certifications critical to our customers, as well as a state-of-the-art facility and processes that support full supplier audit requirements.

Nu-Tek’s peptones are applicable for use in a wide variety of cell lines including mammalian, insect, and bacterial cultures.  Peptones are a valuable addition to any culture that utilizes the basic components of peptones, polypeptides, free amino acids, carbohydrates, salts/trace minerals, and vitamins as critical media components.^4,5

Nu-Tek’s yeast extracts are applicable for use in a wide variety of cell lines including mammalian, insect, and bacterial cultures. Yeast extracts are a valuable addition to any culture that utilizes polypeptides, free amino acids, carbohydrates, salts/trace minerals, and vitamins as critical media components. Yeast extracts may be used alone but are commonly used in conjunction with animal-free peptones to optimize the nutritional profile of the media.

Yes, Nu-Tek’s peptones (hydrolysates) and yeast extracts can be added to complex or chemically defined media, including animal-based (FBS-containing) media. Customers have seen improved performance of existing media when supplementing with peptones. Additionally, Nu-Tek’s products may provide as-good or better performance in media as the primary nutrient source.

Chemically defined media implies that all components and their concentrations are known.  This may involve adding dozens or more components to achieve the required nutritional profile.  Peptones are considered “complex” media components as they contain multiple nutritionally valuable components, not all of which may be fully defined.  Nu-Tek controls this biological variability through a state-of-the-art, proprietary manufacturing process, as well as our Variability Reduction Program (VRP) to optimize and define these complex materials.

Nu-Tek products provide comparable or better performance to other media supplements commonly found in the market. Customers using Nu-Tek’s products benefit from this performance profile as well as the ability to eliminate contamination risk, secure supply chain, and leverage Nu-Tek’s variability reduction expertise.

Peptones and yeast extracts provide diverse nutrition, simplifying media development and production by supporting multiple cell culture functions.  In contrast with animal-derived additives, such as fetal bovine serum (FBS), animal-free peptones/yeast extracts have improved lot to lot consistency and definition while eliminating adventitious agent risk.

In comparison to some chemically-defined media additives, peptones readily dissolve at standard process conditions, reducing the need for alkaline or dual feeds.  Peptones have a well-established history of regulatory acceptance and safety, as evidenced by their use in approved therapeutic manufacturing processes.

Peptones are derived from plant flours and yeasts. While there is minor natural variability due to the biological source of each product, Nu-Tek’s state-of-the-art facility and processes, equipped with industry-leading monitoring and controls, provides industry-leading consistency lot to lot.

Nu-Tek produces every product in its 100% animal-free, state-of-the-art manufacturing facility. Our industry-leading monitoring and controls provide tight control of product variability lot to lot, and allow us to customize products through our Variability Reduction Program (VRP) should customers require tailored material specifications.

Nu-Tek’s Variability Reduction Program (VRP) is an industry-leading platform leveraged by customers to define, refine, and control Nu-Tek product attributes critical to a customer’s production process. This service is a formal collaboration between Nu-Tek and our customers to achieve customized product specifications needed to meet optimal performance, quality, and regulatory requirements. We invite you to connect with our team to learn more about our VRP and how it could serve your production needs.

Nu-Tek’s VRP is intended for customers using or interested in using Nu-Tek’s products. Whether a customer is establishing a new media, improving the performance of existing formulations, or seeking secondary sourcing opportunities, Nu-Tek’s VRP can facilitate selecting the ideal raw material. Contact our team of experts to discuss what the Program can do to support your company’s goals.

Nu-Tek can customize products depending on customer requirements. From packaging to adjusting Critical Material Attributes (CMAs) through our Variability Reduction Program, Nu-Tek is your partner in secure, reliable, animal-free peptones (hydrolysates) and yeast extracts.

Nu-Tek works directly with customers to ensure competitive pricing. Most Nu-Tek customers require industrial-scale quantities of our products and we are happy to provide pricing options based on product requirements and volumes; contact our team for more information regarding purchase volumes and pricing.